Biomedical Engineering - Carnegie Mellon University

Books

Biomaterials & Biotechnology

Biopolymers & Nanotechnology

Rosalyn Abbott* Tissue engineering, adipose microenvironments, disease modelling, tissue regeneration, natural biomaterials, silk, engineering the extracellular matrix
Chris J. Bettinger* BioMEMS for tissue regeneration; biodegradable electronic devices; biomimetic tissue-device interfaces; biomaterials synthesis; microfabrication of biomaterials
Tzahi Cohen-Karni* Nano-biotechnology; nano–bio interfaces; nanomaterials synthesis; biomedical applications of nanowires/nanotubes; biomedical nanodevices/sensors
Kris N. Dahl Mechanics of the cell nucleus in normal and disease states; nuclear mechanics in stem cell differentiation and cancer progression; mechanotransduction; cellular interactions with nanomaterials
Adam W. Feinberg* Tissue regeneration in neuromuscular and cardiovascular systems; self-assembly and multi-scale coupling in biological systems; cell-material interactions; protein-based materials; bioprosthetics; stem cell differentiation and engineered morphogenesis
K. Jimmy Hsia* Bionanotechnology; electro-mechanical coupling of carbon nanotubes and nanotube composites
Philip R. LeDuc* Biological mechanical systems; mechanotransduction; biological microfluidics and MEMS; molecular micropatterning
Michael E. McHenry Magnetic nanoparticles for tagging cells and MRI enhancement; cellular interactions with nanocrystalline magnetic materials; cellular effects of RF heating of magnetic nanoparticles; applications of magnetic nanoparticles and ferrogels in tissue engineering
Xi (Charlie) Ren* Whole-organ bioengineering; extracellular matrix engineering; vascular endothelial heterogeneity; stem cell-based directed tissue morphogenesis
Alan J. Russell Development of enzyme-polymer hybrid materials; exploiting the interface of chemistry, biology and materials for tissue engineering
Stefanie Sydlik Polymer synthesis; polymer synthesis; biomimetic polymers and materials; graphene biomaterials; surgical adhesives; covalent controlled release; stem cells; bone and cartilage regeneration
Robert D. Tilton* Nanoparticle probes; nanoparticle-cell interactions; environmental effects of nanoparticles; surfactant-based carriers for pulmonary drug delivery; protein adsorption and protein drug delivery; cell sorting technologies
Yu-li Wang* Mechanisms of cell migration and division; cellular mechanical activities; mechanics of cell-matrix interactions; mechanotransduction; live cell imaging and image processing; cellular micromanipulations
Newell R. Washburn* Bioactive polymers for wound healing and regenerative medicine; biopolymer mediated manipulations of cytokines and growth factors
Kathryn A. Whitehead Drug delivery; biomaterial design and synthesis; transport in biological systems; RNA interference therapeutics

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Interfacial Biotechnology & Drug Delivery

Keith E. Cook* Artificial lungs; hemodynamics; pulmonary drug delivery; liquid ventilation; right ventricular function; critical care medicine
Jonathan Minden Technologies for proteomics; devices to couple gel electrophoresis to mass spectrometry; automation of 2D gel electrophoresis; protein capture for proteomics sample preparation; applications of image analysis in proteomics
Todd M. Przybycien* CMOS-MEMS-based biosensors; protein structure characterization; processing of pharmaceutical proteins; protein drug delivery
Alan J. Russell Development of enzyme-polymer hybrid materials; exploiting the interface of chemistry, biology and materials for tissue engineering
James W. Schneider Nanoemulsions for DNA separation; novel biomimetic materials for bioseparation and biosensing
Robert D. Tilton* Nanoparticle probes; nanoparticle-cell interactions; environmental effects of nanoparticles; surfactant-based carriers for pulmonary drug delivery; protein adsorption and protein drug delivery; cell sorting technologies
Kathryn A. Whitehead Drug delivery; biomaterial design and synthesis; transport in biological systems; RNA interference therapeutics

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Microfabrication, Micropatterning & Microdevices

Chris J. Bettinger* BioMEMS for tissue regeneration; biodegradable electronic devices; biomimetic tissue-device interfaces; biomaterials synthesis; microfabrication of biomaterials
Tzahi Cohen-Karni* Nano-biotechnology; nano–bio interfaces; nanomaterials synthesis; biomedical applications of nanowires/nanotubes; biomedical nanodevices/sensors
Phil G. Campbell* Bioavailability and proteolytic processing of growth factors; musculoskeletal tissue repair and regeneration; biomimetic tissue engineering materials
Gary K. Fedder Design and fabrication of integrated micro/nano-scale sensors and actuator; implantable microsystems; neural probe arrays
Adam W. Feinberg* Tissue regeneration in neuromuscular and cardiovascular systems; self-assembly and multi-scale coupling in biological systems; cell-material interactions; protein-based materials; bioprosthetics; stem cell differentiation and engineered morphogenesis
K. Jimmy Hsia* Nanotechnology for biosensing and bioactuation; electro-mechanical coupling of carbon nanotubes and nanotube composites
Philip R. LeDuc* Biological mechanical systems; mechanotransduction; biological microfluidics and MEMS; molecular micropatterning
Carmel Majidi Soft-matter engineering; stretchable electronics; soft robotics; wearable computing
Todd M. Przybycien* CMOS-MEMS-based biosensors; protein structure characterization; processing of pharmaceutical proteins; protein drug delivery
Rebecca Taylor Micro- and nanoscale force sensors; MEMS
Yu-li Wang* Mechanisms of cell migration and division; cellular mechanical activities; mechanics of cell-matrix interactions; mechanotransduction; live cell imaging and image processing; cellular micromanipulations
Lee E. Weiss Computer vision-based cell tracking; bioprinting for tissue engineering; biofabrication; protein-based plastics; biodegradable electronics

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*Asterisk indicates core faculty

Cell & Tissue Engineering

Biosensors for Cell & Tissue Imaging

Bruce A. Armitage Luminescent probes for cell imaging; probes for manipulating gene expression
Marcel P. Bruchez Fluorescent probes for cell imaging; luminescent nanocrystal probes
Chien Ho Contrast agents for MRI-based cell tracking
Michael E. McHenry Magnetic nanoparticles for tagging cells and MRI enhancement; cellular interactions with nanocrystalline magnetic materials; cellular effects of RF heating of magnetic nanoparticles; applications of magnetic nanoparticles and ferrogels in tissue engineering
Alan S. Waggoner Optical biosensors for cell imaging and high throughput assays

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Cellular/Molecular Mechanics & Engineering

Kris N. Dahl Mechanics of the cell nucleus in normal and disease states; nuclear mechanics in stem cell differentiation and cancer progression; mechanotransduction; cellular interactions with nanomaterials
Michael M. Domach High throughput systems for cell growth analysis; optimization of bioreactor performance
Adam W. Feinberg* Tissue regeneration in neuromuscular and cardiovascular systems; self-assembly and multi-scale coupling in biological systems; cell-material interactions; protein-based materials; bioprosthetics; stem cell differentiation and engineered morphogenesis
K. Jimmy Hsia* Cell mechanics and bionanotechnology; nanoscale features and their effects on mechanical behavior in biological materials
Phil R. LeDuc* Biological mechanical systems; mechanotransduction; biological microfluidics and MEMS; molecular micropatterning
Mathias Loesche Molecular biophysics; engineering of model membranes; biophysical mechanism of disease; functional, structural and dynamic characterization of protein-membrane interaction
Rebecca Taylor Mechanobiology; micro- and nanoscale force sensors; cardiovascular biomechanics
Yu-li Wang* Mechanisms of cell migration and division; cellular mechanical activities; mechanics of cell-matrix interactions; mechanotransduction; live cell imaging and image processing; cellular micromanipulations
Ge Yang* Computer vision techniques for biological microscopy images; quantitative analysis and computational modeling of dynamic cellular processes and signaling events; intracellular transport in neurons in normal physiology and neurodegenerative diseases; cytoskeletal dynamics in cell division; advanced fluorescence imaging and image analysis of live cells

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Tissue Engineering

Rosalyn Abbott* Tissue engineering, adipose microenvironments, disease modelling, tissue regeneration, natural biomaterials, silk, engineering the extracellular matrix
Chris J. Bettinger* BioMEMS for tissue regeneration; biodegradable electronic devices; biomimetic tissue-device interfaces; biomaterials synthesis; microfabrication of biomaterials
Phil G. Campbell Bioavailability and proteolytic processing of growth factors; musculoskeletal tissue repair and regeneration; biomimetic tissue engineering materials
Adam W. Feinberg* Tissue regeneration in neuromuscular and cardiovascular systems; self-assembly and multi-scale coupling in biological systems; cell-material interactions; protein-based materials; bioprosthetics; stem cell differentiation and engineered morphogenesis
Carmel Majidi Soft-matter engineering; stretchable electronics; soft robotics; wearable computing
Xi (Charlie) Ren* Whole-organ bioengineering; extracellular matrix engineering; vascular endothelial heterogeneity; stem cell-based directed tissue morphogenesis
Alan J. Russell Development of enzyme-polymer hybrid materials; exploiting the interface of chemistry, biology and materials for tissue engineering
Stefanie Sydlik Stem cells; bone and cartilage regeneration
Newell R. Washburn* Bioactive polymers for wound healing and regenerative medicine; biopolymer mediated manipulations of cytokines and growth factors
Lee E. Weiss Computer vision-based cell tracking; bioprinting for tissue engineering; biofabrication; protein-based plastics; biodegradable electronics

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*Asterisk indicates core faculty

Imaging & Signal Processing

Biological Imaging & Image Informatics

Chien Ho Migration of immune cells in vivo; immune response to organ transplantation; MRI-based in vivo imaging
Jelena Kovacevic Processing and analysis of microscope images; multiresolution/multiscale image processing methods; processing and analysis of medical images
Jonathan Minden Technologies for proteomics; devices to couple gel electrophoresis to mass spectrometry; automation of 2D gel electrophoresis; protein capture for proteomics sample preparation; applications of image analysis in proteomics
Robert F. Murphy Applications of machine learning in biological imaging; automated construction of generative models of cell organization from complex cellular images; active machine learning for driving biomedical experimentation
Yu-li Wang* Mechanisms of cell migration and division; cellular mechanical activities; mechanics of cell-matrix interactions; mechanotransduction; live cell imaging and image processing; cellular micromanipulations
Ge Yang* Computer vision techniques for biological microscopy images; quantitative analysis and computational modeling of dynamic cellular processes and signaling events; intracellular transport in neurons in normal physiology and neurodegenerative diseases; cytoskeletal dynamics in cell division; advanced fluorescence imaging and image analysis of live cells

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Medical Imaging & Image Processing

Yang Cai Video analytics; interactive visualization; virtual reality; endoscopic imaging; 3D surface imaging and reconstruction; digital human modeling; biomedical games; ambient diagnostics; pill camera; smart fiber; smart home; personal robot; privacy algorithms; social media and health
John Galeotti Novel optics for imaging and visualization; biomedical image analysis and visualization; combining robotic multi-camera computer vision with volumetric/tomographic biomedical imaging modalities; Optical Coherence Tomography (OCT)
Jana Kainerstorfer* Biomedical photonics; diffuse optical imaging; clinical translation of optical imaging methods; microvascular imaging; disease diagnostics and treatment monitoring; imaging of brain functions
Jelena Kovacevic Processing and analysis of medical images
Jose M. F. Moura Post processing and interpretation of medical images; automated image segmentation; registration, classification, and interpretation; MRI imaging; microwave non-invasive imaging
George D. Stetten Statistics and geometry of image analysis; psychophysics of image perception/cognition; medical image guidance with in-situ virtual images; fingertip visual to haptic transducers
Y. Jessica Zhang Finite element method and its applications in biomechanics; image-based geometric modeling and mesh generation; image processing and analysis; patient-specific geometric modeling for cardiovascular surgical planning; geometric modeling and active site detection for molecular/protein structures; geometric modeling and mesh generation from medical imaging data; computer-assisted surgery

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Neural Computation & Associated Devices

Steven M. Chase* Information representation in neural systems; brain-computer interfaces; neural signal processing; learning, adaptation, and motor control
Gary K. Fedder Design and fabrication of integrated micro/nano-scale sensors and actuators; implantable microsystems; neural probe arrays
Hartmut Geyer Biomechanics and motor control of human locomotion; design and control of powered segmented legs in robotics and rehabilitation
Jana Kainerstorfer* Near IR diffuse optical imaging of brain functions
Shawn Kelly Retinal prostheses for the blind; neural prostheses; neural stimulation circuitry; wireless power and data telemetry for medical devices; hermetic packaging for medical devices
Burak Ozdoganlar Micro- and nano-manufacturing; medical device fabrication; surgical engineering; neural probes fabrication; microneedle arrays for transdermal delivery; bone drilling analysis
Byron Yu* Neural signal processing; machine learning approaches in neuroscience; neural prosthetic systems

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*Asterisk indicates core faculty

Medical Devices & Robotics

Cardiovascular Mechanics & Devices

James F. Antaki* Experimental and computational cardiac fluid dynamics; rheology of blood and mechanics of the heart muscle; computational medical device design and optimization; pediatric and adolescent artificial hearts; cardiac surgical planning
Keith E. Cook* Artificial lungs; hemodynamics; pulmonary drug delivery; liquid ventilation; right ventricular function; critical care medicine
Jana Kainerstorfer* Microvascular imaging and associated devices
Xi (Charlie) Ren* Whole-organ bioengineering; extracellular matrix engineering; vascular endothelial heterogeneity; stem cell-based directed tissue morphogenesis
Dennis Trumble* Computational cardiac mechanics; cardiac assist devices; muscle-powered implants; medical device design and optimization; tissue-device interfaces; the neural basis of cognition; science education
Conrad M. Zapanta* Prosthetic cardiac valves; cardiac assist devices; biomedical engineering education
Y. Jessica Zhang Finite element method and its applications in biomechanics; image-based geometric modeling and mesh generation; image processing and analysis; patient-specific geometric modeling for cardiovascular surgical planning; geometric modeling and active site detection for molecular/protein structures; geometric modeling and mesh generation from medical imaging data; computer-assisted surgery

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Surgical Engineering & Robotics

James F. Antaki* Experimental and computational cardiac fluid dynamics; rheology of blood and mechanics of the heart muscle; computational medical device design and optimization; pediatric and adolescent artificial hearts; cardiac surgical planning
Howie Choset Surgical robotics; snake robots; path planning; motion control; mapping
Burak Ozdoganlar Micro- and nano-manufacturing; medical device fabrication; surgical engineering; neural probes fabrication; microneedle arrays for transdermal delivery; bone drilling analysis
Yoed Rabin Heat and mass transfer in biological systems; mechanical aspects of cryobiology; cryopreservation; cryosurgery devices & techniques; computerized planning of cryosurgery
Cameron Riviere Robotics for microsurgery and minimally invasive surgery; precision tracking in microsurgery
Kenji Shimada Medical robotics; computer-assisted surgery; human body modeling and simulation
George D. Stetten Statistics and geometry of image analysis; psychophysics of image perception/cognition; medical image guidance with in-situ virtual images; fingertip visual to haptic transducers
Lee E. Weiss Computer vision-based cell tracking; bioprinting for tissue engineering; biofabrication; protein-based plastics; biodegradable electronics
Y. Jessica Zhang Finite element method and its applications in biomechanics; image-based geometric modeling and mesh generation; image processing and analysis; patient-specific geometric modeling for cardiovascular surgical planning; geometric modeling and active site detection for molecular/protein structures; geometric modeling and mesh generation from medical imaging data; computer-assisted surgery

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*Asterisk indicates core faculty