Research
 

Portfolio

Fundamental Principles of Biomedical Engineering

Biomechanics

James F. Antaki

Experimental and computational cardiac fluid dynamics; rheology of blood and mechanics of the heart muscle

Kris N. Dahl

Mechanics of the cell nucleus in normal and disease states; nuclear mechanics in stem cell differentiation and cancer progression; mechanotransduction

Ender A. Finol

Fluid mechanics of the cardiovascular system; biomechanics of vascular aneurysms; continuum mechanics modeling of growth and remodeling of aneurysms

Philip R. LeDuc

Molecular and cellular biomechanics; mechanotransduction

Maumita Mandal

Mechanics of single RNA molecules and RNA-small molecule interactions

Kerem Pekkan

Cardiovascular fluid dynamics in embryonic, normal, and diseased states; fluid-tissue interactions

Yoed Rabin

Heat and mass transfer in biological systems; mechanical aspects of cryobiology; cryopreservation

Yu-li Wang

Mechanisms of cell division and migration; mechanics of cell-matrix interactions; mechanotransduction

Ge Yang

Cell molecular mechanics; mechanics of cell division; function and regulation of motor proteins in intracellular transport

Y. Jessica Zhang

Finite element method and its applications in biomechanics; geometric modeling and active site detection for molecular/protein structures

Additional Areas

Phil G. Campbell

Bioavailability and proteolytic processing of growth factors

Justin C. Crowley

Formation of neural circuitry in the visual system

Chien Ho

Migration of immune cells in vivo; immune response to organ transplantation

Mathias Loesche

Molecular biophysics; biophysical mechanism of disease; functional, structural and dynamic characterization of protein-membrane interaction

Enabling Technologies for Biomedical Research

 Bioimaging and Biomedical Signal Processing

Bruce A. Armitage

Luminescent probes for cell imaging; probes for manipulating gene expression

Marcel P. Bruchez

Fluorescent probes for cell imaging; luminescent nanocrystal probes

Ender A. Finol

Segmentation algorithms for medical imaging

Chien Ho

MRI-based in vivo imaging

Takeo Kanade

Computer vision-based object tracking in microscopic images

Jelena Kovacevic

Image processing and analysis; multiresolution/multiscale image processing methods

Michael E. McHenry

Magnetic nanoparticles for tagging cells and MRI enhancement

Maumita Mandal

Single molecular mechanical manipulations; optical twizzers

Robert F. Murphy

Applications of machine learning in biological imaging; automated extraction of knowledge from complex cellular images

Gustavo K. Rohde

Automated image modeling; automated annotation of biological images; methods for image registration, segmentation, detection, and estimation

George D. Stetten

Statistics and geometry of image analysis; psychophysics of image perception/cognition

Yu-li Wang

Live cell imaging; image processing in fluorescence imaging; micromanipulation

Alan S. Waggoner

Optical biosensors for cell imaging and high throughput assays

Lee E. Weiss

Computer vision-based cell tracking

Ge Yang

Bioimage informatics; computer vision for live cell imaging; computational and statistical analysis of cell dynamics; single molecular imaging

Byron Yu

Neural signal processing; machine learning approaches in neuroscience

Stefan Zappe

High-throughput confocal fluorescence imaging technologies for cell/embryo-based screens

Y. Jessica Zhang

Geometric modeling and mesh generation of biomedical images; biomedical image processing and analysis

Additional Areas

Michael M. Domach

High throughput systems for cell growth analysis

Technologies at the Interface of Biological and Artificial Materials

Nanobiotechnology and Bio-MEMS


Kris N. Dahl

Cellular interactions with nanomaterials

Michael E. McHenry

Cellular interactions with nanocrystalline magnetic materials; cellular effects of RF heating of magnetic nanoparticles

Philip R. LeDuc

Biological microfluidics and MEMS; molecular micropatterning

Mathias Loesche

Engineering of model membranes

Todd M. Przybycien

CMOS-MEMS-based biosensors

James W. Schneider

Nanoemulsions for DNA separation; novel biomimetic materials for bioseparation and biosensing

Metin Sitti

Nanoprobe based robots for micromanipulation

Robert D. Tilton

Nanoparticle probes; nanoparticle-cell interactions; environmental effects of nanoparticles

Stefan Zappe

Bio-MEMS for automated cell handling and manipulation; synthesis of nanoparticles for labeling and MRI tracking of stem cells and drug/gene deliveries

Additional Areas

Michael M. Domach

Optimization of bioreactor performance

Jeanne M. VanBriesen

Pathogen detection; biofilm formation

Innovative Engineering for Medicine

Cardiovascular Device Design

James F. Antaki Computational medical device design and optimization; pediatric and adolescent artificial hearts; cardiac surgical planning
Ender A. Finol   

Design and assessment of cerebral protection devices and intravascular thrombectomy devices

Kerem Pekkan

Cardiovascular surgical planning; biomimetic circulation systems

Conrad M. Zapanta   

 Prosthetic cardiac valves, cardiac assist devices

Drug Delivery

Todd M. Przybycien

Protein structure characterization; processing of pharmaceutical proteins; protein drug delivery

Robert D. Tilton

Surfactant-based carriers for pulmonary drug delivery; protein adsorption and protein drug delivery; cell sorting technologies

Medical Image Processing

Jelena Kovacevic

Processing and analysis of medical images

Jose M. F. Moura

Post processing and interpretation of medical images; automated image segmentation; registration, classification, and interpretation; MRI imaging; microwave non-invasive imaging

Robert F. Murphy

Automated analysis of subcellular patterns in tissue images

Gustavo K. Rohde

Automated digital pathology

George D. Stetten 

Medical image guidance with in-situ virtual images; fingertip visual to haptic transducers

Surgical Engineering and Medical Robotics

Howie Choset

Surgical robotics; snake robots; path planning; motion control; mapping

Branislav Jaramaz

Computer-assisted surgery; surgical planning and simulation

Takeo Kanade

Computer-assisted surgery

Yoed Rabin

Cryosurgery devices & techniques; computerized planning of cryosurgery

Cameron Riviere

Robotics for microsurgery and minimally invasive surgery; precision tracking in microsurgery

Kenji Shimada

Computer-assisted surgery; human body simulation

Metin Sitti

Microrobotics for diagnosis and surgery

Byron Yu

Neural prosthetic systems

Y. Jessica Zhang

Patient-specific geometric modeling for cardiovascular surgical planning; computer-assisted surgery

Regenerative Medicine

Phil G. Campbell

Musculoskeletal tissue repair and regeneration; biomimetic tissue engineering materials

Jeffrey O. Hollinger

Bone tissue engineering involving biomaterials, biologicals, imaging, histology-histomorphometry, in vitro and in vivo animal models; repair of bone fracture and gaps

Michael E. McHenry

Applications of magnetic nanoparticles and ferrogels in tissue engineering

Newell R. Washburn

Bioactive polymers for wound healing and regenerative medicine; biopolymer mediated manipulations of cytokines and growth factors

Lee E. Weiss

Bioprinting for tissue engineering; biofabrication; protein-based plastics; biodegradable electronics

Stefan Zappe

Stem cell systems biology and engineering; generation of complex modular tissue engineering constructs

 

 
 
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