Research

"Sensing and Actuating Life"

 

Research Portfolio

I. Fundamentals of Biomedical Engineering

II. Enabling Technologies for Biomedical Research

III. Technologies at the Interface of Biological and Artificial Materials

IV. Innovative Engineering for Medicine

I. Fundamentals of Biomedical Engineering

Fundamentals of Cell/Tissue Engineering and Biomolecular/Cellular Mechanics

Kris N. Dahl Mechanics of the cell nucleus in normal and disease states; nuclear mechanics in stem cell differentiation and cancer progression; mechanotransduction
Adam W. Feinberg Self-assembly and multi-scale coupling in biological systems
Chien Ho Migration of immune cells; immune response to organ transplantation
Philip R. LeDuc Molecular and cellular biomechanics; mechanotransduction
Mathias Loesche Molecular biophysics; biophysical mechanism of disease; functional, structural and dynamic characterization of protein-membrane interaction
Maumita Mandal Mechanics of single RNA molecules and RNA-small molecule interactions
Yu-li Wang Cell migration in tissue formation and cancer invasion; generation and function of cellular mechanical forces; cellular responses to mechanical and topographical cues
Ge Yang quantitative
Analysis and computational modeling of dynamic cellular processes and signaling events; intracellular transport in neurons in normal physiology and neurodegenerative diseases; cytoskeletal dynamics in cell division

[Top]

Tissue/Cardiovascular Biomechanics and Bio-Fluid Mechanics

James F. Antaki Experimental and computational cardiac fluid dynamics; rheology of blood and mechanics of the heart muscle
Hartmut Geyer Biomechanics and motor control of human locomotion
Kerem Pekkan Cardiovascular fluid dynamics in embryonic, normal, and diseased states; fluid-tissue interactions
Yoed Rabin Heat and mass transfer in biological systems; mechanical aspects of cryobiology; cryopreservation
Y. Jessica Zhang Application of finite element methods to biomechanics; geometric modeling and active site detection for molecular/protein structures
(Mehrdad Massoudi) Biomechanics; rheology of blood and mechanics of the heart muscle; non-linear constitutive modeling of biological tissues; mechanics of complex fluids

[Top]

Additional Areas

Phil G. Campbell Bioavailability and proteolytic processing of growth factors
Justin C. Crowley Formation of neural circuitry in the visual system

II. Enabling Technologies for Biomedical Research

 Bioimage/Signal Processing and Informatics

Steven M. Chase Information representation in neural systems; neural signal processing
Takeo Kanade Computer vision-based object tracking in microscopic images
Jelena Kovacevic Image processing and analysis; multiresolution/multiscale image processing methods
Robert F. Murphy Applications of machine learning in biological imaging; automated extraction of knowledge from complex cellular images
Gustavo K. Rohde Automated image modeling; automated annotation of biological images; methods for image registration, segmentation, detection, and estimation
George D. Stetten Statistics and geometry of image analysis; psychophysics of image perception/cognition
Lee E. Weiss Computer vision-based cell tracking
Ge Yang Computer vision techniques for biological microscopy images; advanced fluorescence imaging and image analysis of live cells
Byron Yu Machine learning approaches in neuroscience
Y. Jessica Zhang Geometric modeling and mesh generation of biomedical images; biomedical image processing and analysis
(John Galeotti) Novel optics for imaging and visualization; biomedical image analysis and visualization

[Top]

Fluorescence Imaging and MRI Technologies

Bruce A. Armitage Luminescent probes for cell imaging; probes for manipulating gene expression
Marcel P. Bruchez Fluorescent probes for cell imaging; luminescent nanocrystal probes
Chien Ho MRI-based in vivo imaging
Michael E. McHenry Magnetic nanoparticles for tagging cells and MRI enhancement
Maumita Mandal Single molecular mechanical manipulations; optical twizzers
Yu-li Wang Live cell imaging; image processing in optical microscopy; cellular micromanipulations
Alan S. Waggoner Optical biosensors for cell imaging and high throughput assays
Stefan Zappe High-throughput confocal fluorescence imaging technologies for cell/embryo-based screens

[Top]

Additional Areas

Michael M. Domach High throughput systems for cell growth analysis

III. Technologies at the Interface of Biological and Artificial Materials

Biomedical Applications of Polymers and Nanomaterials


Kris N. Dahl		 Cellular interactions with nanomaterials
Adam W. Feinberg Cell-material interactions; protein-based materials
Michael E. McHenry Cellular interactions with nanocrystalline magnetic materials; cellular effects of RF heating of magnetic nanoparticles
Mathias Loesche Engineering of model membranes
Alan J. Russell Development of enzyme-polymer hybrid materials
James W. Schneider Nanoemulsions for DNA separation; novel biomimetic materials for bioseparation and biosensing
Robert D. Tilton Nanoparticle probes; nanoparticle-cell interactions; environmental effects of nanoparticles
Newell R. Washburn Novel polymers for biomedical applications
Kathryn A. Whitehead Biomaterial design and synthesis

[Top]

Bio-MEMS and Biosensors

Christopher J. Bettinger Biodegradable electronic devices; biomimetic tissue-device interfaces; microfabrication of biomaterials; biomaterials synthesis
Gary K. Fedder Design and fabrication of integrated micro/nano-scale sensors and actuators, implantable microsystems
Philip R. LeDuc Biological microfluidics and MEMS; molecular micropatterning
Todd M. Przybycien CMOS-MEMS-based biosensors
Metin Sitti Nanoprobe based robots for micromanipulation
Yu-li Wang Applications of Bio-MEMS and artificial hydrogels in cellular manipulation and tissue formation
Stefan Zappe Bio-MEMS for automated cell handling and manipulation; synthesis of nanoparticles for labeling and MRI tracking of stem cells and drug/gene deliveries

[Top]

Additional Areas

Michael M. Domach Optimization of bioreactor performance
Jeanne M. VanBriesen Pathogen detection; biofilm formation

IV. Innovative Engineering for Medicine

Cardiovascular Engineering and Device Design

James F. Antaki Computational medical device design and optimization; pediatric and adolescent artificial hearts; cardiac surgical planning
Kerem Pekkan Cardiovascular surgical planning; biomimetic circulation systems
Conrad M. Zapanta Prosthetic cardiac valves, cardiac assist devices
(Dennis Trumble) Computational cardiac mechanics; cardiac assist devices; muscle-powered implants; medical device design and optimization; pediatric artificial hearts; micro-CT imaging
(John Pacella) Microcirculation; hemodynamics; physiology and RBC distribution; coronary physiology; vascular biology and vulnerable plaque; medical devices pertaining to cardiac assist and interventional cardiology; fluid mechanics

[Top]

Drug Delivery

Todd M. Przybycien Protein structure characterization; processing of pharmaceutical proteins; protein drug delivery
Robert D. Tilton Surfactant-based carriers for pulmonary drug delivery; protein adsorption and protein drug delivery; cell sorting technologies
Kathryn A. Whitehead Transport in biological systems; delivery of RNA interference therapeutics
(Timothy Corcoran) Aerosol drug delivery and aerosol-based nuclear medicine imaging of the lung; therapeutics development for cystic fibrosis and lung transplantation; pulmonary physiology and bioengineering

[Top]

Medical Image Processing and Neural Engineering

Steven M. Chase Brain-computer interfaces; learning, adaptation, and motor control
Gary K. Fedder Neural probe arrays
Jelena Kovacevic Processing and analysis of medical images
Jose M. F. Moura Post processing and interpretation of medical images; automated image segmentation; registration, classification, and interpretation; MRI imaging; microwave non-invasive imaging
Robert F. Murphy Automated analysis of subcellular patterns in tissue images
Thanassis Rikakis Post stroke rehabilitation, virtual/physical mixed  reality rehabilitation, kinematic based evaluation of movement rehabilitation, experience-dependent neural plasticity
Gustavo K. Rohde Automated digital pathology
George D. Stetten Medical image guidance with in-situ virtual images; fingertip visual to haptic transducers
Byron Yu Neural signal processing and neural prosthetic systems
(John Galeotti) Combining robotic multi-camera computer vision with volumetric/tomographic biomedical imaging modalities; Optical Coherence Tomography (OCT)
(Shawn Kelly) Retinal prostheses for the blind; neural prostheses; neural stimulation circuitry; wireless power and data telemetry for medical devices;  hermetic packaging for medical devices
(Mark Doyle) Cardiovascular MRI; rapid imaging approaches; quantitative velocity imaging; improved decision modeling using image data

(John A. Ozolek)

Image analysis; digital pathology; pediatric pathology; otorhinolaryngologic pathology; neonatal diseases; stem cells; teratomas

[Top]

Medical Robotics and Surgical Engineering

Howie Choset Surgical robotics; snake robots; path planning; motion control; mapping
Hartmut Geyer Design and control of powered segmented legs in robotics and rehabilitation
Branislav Jaramaz Computer-assisted surgery; surgical planning and simulation
Takeo Kanade Computer-assisted surgery
Yoed Rabin Cryosurgery devices techniques; computerized planning of cryosurgery
Burak Ozdoganlar Micro- and nano-manufacturing; medical device fabrication; surgical engineering; neural probes fabrication;  microneedle arrays for transdermal delivery; bone drilling analysis
Cameron Riviere Robotics for microsurgery and minimally invasive surgery; precision tracking in microsurgery
Kenji Shimada Computer-assisted surgery; human body simulation
Metin Sitti Microrobotics for diagnosis and surgery
Y. Jessica Zhang Patient-specific geometric modeling for cardiovascular surgical planning; computer-assisted surgery
(Boyle Cheng) Spine biomechanics and neurosciences; comparative test methodologies; ASTM international test standards; clinical robotics; specimen specific dynamic models

[Top]

Regenerative Medicine

Christopher J. Bettinger BioMEMS for tissue regeneration
Phil G. Campbell Musculoskeletal tissue repair and regeneration; biomimetic tissue engineering materials
Adam W. Feinberg Tissue regeneration in neuromuscular and cardiovascular systems; bioprosthetics; stem cell differentiation and engineered morphogenesis
Jeffrey O. Hollinger Bone formulation modulation and engineering using biomaterials, biologicals, imaging, histology-histomorphometry, in vitro and in vivo animal models; regenerating bone fractures and gaps
Michael E. McHenry Applications of magnetic nanoparticles and ferrogels in tissue engineering
Alan J. Russell Exploiting the interface of chemistry, biology and materials for tissue engineering
Newell R. Washburn Promotion of wound healing using bioactive polymers; biopolymer mediated manipulations of cytokines and growth factors
Lee E. Weiss Bioprinting for tissue engineering; biofabrication; protein-based plastics; biodegradable electronics
Stefan Zappe

Stem cell systems biology and engineering; generation of complex modular tissue engineering constructs

[Top]

(parentheses indicate adjunct faculty)

(bold indicates office at Carnegie Mellon University)

(Updated 11/02/2012)

 

RESEARCH

Campus Office for Student Affairs and Graduate Admissions
Department of Biomedical Engineering
Carnegie Mellon University
Doherty Hall 2100
5000 Forbes Avenue
Pittsburgh, PA 15213

Ph: (412) 268-3955
Fax: (412) 268-1173

Administrative Office
Department of Biomedical Engineering
Carnegie Mellon University
PTC 4105
700 Technology Drive
Pittsburgh, PA 15219

Ph: (412) 268-6222
Fax: (412) 268-9807